Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin not only assists in various metabolic reactions but also helps to transfercarbon dioxide. Biotin may also be helpful in maintaining a steady blood sugar level.^[3] Biotin is often recommended for strengthening hair and nails.^{[citation needed]} As a consequence, it is found in many cosmetics and health products for the hair and skin, though it cannot be absorbed through the hair or skin itself.^{[citation needed]}

Biotin deficiency is rare because, in general, intestinal bacteria produce biotin in excess of the body’s daily requirements. For that reason, statutory agencies in many countries, for example the USA^[4] and Australia,^[5] do not prescribe a recommended daily intake of biotin. However, a number of metabolic disorders in which an individual’s metabolism of biotin is abnormal exist.

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